Scientific Programme

Scientific Programme

Tuesday 25 November 2014



Pre-Congress Meeting: Reunião da ASPIC com associações de doentes

Chairs: Manuel Sobrinho Simões, Jorge Soares, Alfredo Carrato, Leonor David


12.30    Registration and Poster mounting




Opening Session


Symposium I: Early cancer detection

Chairs: António Dias Pereira, Carla Oliveira

14.00   Rebecca Fitzgerald . United Kingdom

Changing the face of cancer through early detection: examples of new technologies for oesophageal cancer         

15.00   selected oral presentations

Pedro Castelo-Branco . Tert Hypermethylated Oncological Region - THOR predicts biochemical relapse amongst prostate cancer patients.

José Luis Costa . Detection of somatic alterations in plasma from lung cancer patients.

Lúcia Brandão . Autonomous electrochemical biosensor for cancer screening.

Hugo Pinheiro . Identification of rare CDH1 non-coding variants in Hereditary Diffuse Gastric Cancer.

Andreia V. Pinho . Loss of Slit-Robo signalling in the pancreas increases the severity of pancreatitis.

Sonia A. Melo . Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis.


16.30   Coffee-Break


Symposium II: New research approaches from ASPIC –ASEICA

Chairs: Alfredo Carrato (Spain), Leonor David (Portugal)

17.00   Manuel Serrano . Spain

Pre-clinical and clinical data on the efficacy of anti-Notch therapies for lung adenocarcinomas

18.00   Paula Soares . Portugal

Telomerase promoter mutations in cancer: an emerging molecular biomarker?

18.30   Goreti Sales . Portugal

New biosensors to monitor cancer biomarkers


19.00 - 19:30 

ASPIC General Assembly



Congress Dinner


Wednesday 26 November 2014


Symposium III:  Cancer genes – What did we learn from them?

Chairs: João Nuno Moreira, Sergio Dias

09.00   Moshe Oren . Israel

The many faces of P53.

10.00   selected oral presentations

Marta Pojo . HOXA9 Promotes Glioblastoma Initiation, Aggressiveness and Resistance to Therapy.

Daniel Ribeiro . Flexible IL-7-mediated regulation of autophagy promotes T-cell acute lymphoblastic leukemia cell viability.

Rita Pinto . Establishment of an inducible cdx2 ko/ki model using zinc finger nucleases: impact on the intestinal phenotype.

Richard Hill . TRIB2-mediated AKT activation provides melanoma cells with a novel regulatory mechanism underlying drug resistance.


11.00     Coffee-break

11.30   Manuel Teixeira . Portugal

Li-Fraumeni syndrome: the prime example of pleiotropism in cancer predisposition.

12.00   Branca Cavaco . Portugal

Identification of familial cancer susceptibility genes – novel genomic approaches.


12.30   Lunch


13.30  Poster session

Chairs: Carla Oliveira, Carmen Jerónimo, Deolinda Pereira, João Barata, João Nuno Moreira, Maria Gomes da Silva, Paulo Matos, Pedro Lazo-Zbikowski, Peter Jordan, Sergio Dias.


Symposium IV:  Mechanisms and implications of tumour heterogeneity

 Chairs: João Barata, José Dinis Silva

14.30   Samuel Aparicio . Canada

EACR sponsored lecture

Clonal evolution and cancer medicine

15.00   selected oral presentations

Carla Oliveira . Through the looking glass: the reversion of EMT.

Claudia C. Faria . Targeting of the HGF/cMET pathway in metastatic medulloblastoma.

Ana-Rita Pedrosa . Blocking Jagged1/2 inhibits prostate tumor development in a murine model of prostate adenocarcinoma (TRAMP).

Marta L. Pinto . Macrophage differentiation is modulated by decellularized human colorectal cancer matrices.

16.00   Luís Costa . Portugal

Cancer Metastases: is bone a useful paradigm?


16.30     Coffee-break



Closing Session

EACR Awards